Check Your Eligibility

KALYDECO is for people with cystic fibrosis (CF) age 4 months and older with at least one mutation in their CF gene that is responsive to KALYDECO. Enter your mutations to see if at least one of them is eligible. You can also use the chart below to determine if you are eligible for KALYDECO. 

4 months and older

See if the CF gene mutation you entered is correct and search again.

You can view the full list of eligible KALYDECO mutations below.

If you don’t know you or your child's CF gene mutations, it’s important to work with your healthcare provider to identify them. Knowing your mutations can help determine if KALYDECO could be right for you. 

Based on the information you entered, you may be eligible for KALYDECO.

Talk with your healthcare provider to see if KALYDECO is right for you.

Here is some information about KALYDECO that may be helpful:

Neither CF gene mutation you entered is eligible for KALYDECO.

Talk with your healthcare provider to discuss your CF care plan and treatment options that may be right for you.

KALYDECO is for the treatment of CF in people age 4 months and older who have one of the following 38 CF gene mutations. If you don't see your mutation in this chart, try using the tool above. 


2789+5G→A D110H F1052V G551S R117H S549R
3272-26A→G D1152H F1074L K1060T R347H S945L
3849+10kbC→T D1270N G1069R L206W R352Q S977F
711+3A→G D579G G1244E P67L R74W  
A1067T E193K G1349D R1070Q S1251N  
A455E E56K G178R R1070W S1255P  
D110E E831X G551D R117C S549N  
2789+5G→A E831X R1070W
3272-26A→G F1052V R117C
3849+10kbC→T F1074L R117H
711+3A→G G1069R R347H
A1067T G1244E R352Q
A455E G1349D R74W
D110E G178R S1251N
D110H G551D S1255P
D1152H G551S S549N
D1270N K1060T S549R
D579G L206W S945L
E193K P67L S977F
E56K R1070Q  


  • The following mutations were not included in the clinical studies but are predicted to respond based on results from a laboratory setting: A1067T, D110E, D110H, D1270N, E56K, E193K, F1052V, F1074L, G1069R, K1060T, R74W, and R1070Q 
  • F508del and 26 other mutations are not responsive to KALYDECO based on clinical and/or laboratory data

Talk to your doctor to learn if you have an indicated CF gene mutation.

It is not known if KALYDECO is safe and effective in children under 4 months of age.

Keep in mind that not all mutations were evaluated in clinical studies, and those that were evaluated were not studied in all age groups. However, KALYDECO is approved for people age 4 months and older with any of the 38 indicated mutations listed above.