Who KALYDECO® Is For
Check Your Eligibility
KALYDECO is for people age 6 months and older with at least one mutation in their cystic fibrosis (CF) gene that is responsive to KALYDECO. Enter your mutations to see if at least one of them is eligible. You can also use the chart below to determine if you are eligible for KALYDECO.
If you don’t know your CF gene mutations, it’s important to work with your healthcare provider to identify them. Knowing your mutations can help determine if KALYDECO could be right for you.
Based on the information you entered, you may be eligible for KALYDECO.
Talk with your healthcare provider to see if KALYDECO is right for you.
Here is some information about KALYDECO that may be helpful:
Neither CF gene mutation you entered is eligible for KALYDECO.
Talk with your healthcare provider to discuss your CF care plan and treatment options that may be right for you.
KALYDECO is for the treatment of CF in people age 6 months and older who have one of the following 38 CF gene mutations. If you don't see your mutation in this chart, try using the tool above.
| 2789+5G→A | D110H | F1052V | G551S | R117H | S549R |
| 3272-26A→G | D1152H | F1074L | K1060T | R347H | S945L |
| 3849+10kBc→T | D1270N | G1069R | L206W | R352Q | S977F |
| 711+3A→G | D579G | G1244E | P67L | R74W | |
| A1067T | E193K | G1349D | R1070Q | S1251N | |
| A455E | E56K | G178R | R1070W | S1255P | |
| D110E | E831X | G551D | R117C | S549N |
| 2789+5G→A | E831X | R1070W |
| 3272-26A→G | F1052V | R117C |
| 3849+10kBc→T | F1074L | R117H |
| 711+3A→G | G1069R | R347H |
| A1067T | G1244E | R352Q |
| A455E | G1349D | R74W |
| D110E | G178R | S1251N |
| D110H | G551D | S1255P |
| D1152H | G551S | S549N |
| D1270N | K1060T | S549R |
| D579G | L206W | S945L |
| E193K | P67L | S977F |
| E56K | R1070Q |
- The following mutations were not included in the clinical studies but are predicted to respond based on results from a laboratory setting: A1067T, D110E, D110H, D1270N, E56K, E193K, F1052V, F1074L, G1069R, K1060T, R74W, and R1070Q
- F508del and 26 other mutations are not responsive to KALYDECO based on clinical and/or laboratory data
Talk to your doctor to learn if you have an indicated CF gene mutation.
It is not known if KALYDECO is safe and effective in children under 6 months of age.
Keep in mind that not all mutations were evaluated in clinical studies, and those that were evaluated were not studied in all age groups. However, KALYDECO is approved for people age 6 months and older with any of the 38 indicated mutations listed above.
