Terms & Conditions

In submitting your quote, story, and/or other material or information (“Material”) to Vertex Pharmaceuticals Incorporated (“Vertex”), you agree to the following terms and conditions as well as the Terms and Conditions for Submissions to Vertex, the Vertex Terms and Conditions of Website Use, and the Vertex Privacy Notice. By making this submission, your submission is subject to, and you represent that you have complied with, all the terms therein. You agree that you were responsible for the creation of this Material, that you or your child have been diagnosed with cystic fibrosis, and that you or your child are taking KALYDECO® (ivacaftor) for an FDA-approved use as prescribed by a healthcare provider.

In submitting this Material, you are confirming that you are 18 years of age or older and that you and your child are US residents. You authorize Vertex and those acting with Vertex's authority and permission to use, display, and modify the Material you submit for general internal and external use by Vertex (including publication on Vertex's websites or in other marketing materials), and you attest that any other person referenced in the Material has done the same. To the extent permitted by law, by submitting the Material, you waive any privacy expectations you may have with regard to the Material and attest that other individuals referenced in the Material have done the same. You understand that Vertex is under no obligation to use any Material submitted and that Vertex may, as a condition of its use of the Material, require that you review and agree to additional contractual terms.

You may contact Vertex with questions or comments about these terms and conditions, or to request access to or correction of your information. See the Vertex Privacy Notice for contact information.

In submitting this Material, you agree to be contacted by Vertex and/or third-party vendors on its behalf for further information and/or to provide photo content to support the Material.  

Thank you for submitting your story.

We will be in touch. Please add PatientStories@vertex-pharmaceuticals.com to your address book so you don’t miss our e-mail.

Share Your Story

We can't wait to hear your KALYDECO® story!

Use the form below to submit your story. Before you start writing, keep these things in mind:

  • Because we work in a regulated industry, we need to ensure that your story is representative of KALYDECO. We may look to work with you to make some edits to your story, if necessary
  • We will follow up with you after your submission. We may also ask you for some photos to help bring your story to life

Important Safety Information

Do not take KALYDECO if you take certain medicines or herbal supplements, such as:

  • the antibiotics rifampin (RIFAMATE®, RIFATER®) or rifabutin (MYCOBUTIN®)
  • seizure medicines such as phenobarbital, carbamazepine (TEGRETOL®, CARBATROL®, and EQUETRO®), or phenytoin (DILANTIN®, PHENYTEK®)
  • St. John’s wort

Talk to your doctor before taking KALYDECO if you take any of the medicines or supplements listed above.

What is KALYDECO® (ivacaftor)?


KALYDECO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients age 4 months and older who have at least one mutation in their CF gene that is responsive to KALYDECO.

Talk to your doctor to learn if you have an indicated CF gene mutation.

It is not known if KALYDECO is safe and effective in children under 4 months of age.

What should I tell my doctor before taking KALYDECO?

Before you take KALYDECO, tell your doctor if you:

  • have liver or kidney problems
  • drink grapefruit juice or eat grapefruit
  • are pregnant or plan to become pregnant. It is not known if KALYDECO will harm your unborn baby. You and your doctor should decide if you will take KALYDECO while you are pregnant
  • are breastfeeding or planning to breastfeed. It is not known if KALYDECO passes into your breast milk. You and your doctor should decide if you will take KALYDECO while you are breastfeeding

KALYDECO may affect the way other medicines work, and other medicines may affect how KALYDECO works.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements, as the dose of KALYDECO may need to be adjusted when taken with certain medications.

Especially tell your doctor if you take:

  • antifungal medications such as ketoconazole (e.g., NIZORAL®), itraconazole (e.g., SPORANOX®), posaconazole (e.g., NOXAFIL®), voriconazole (e.g., VFEND®), or fluconazole (e.g., DIFLUCAN®)
  • antibiotics such as telithromycin (e.g., KETEK®), clarithromycin (e.g., BIAXIN®), or erythromycin (e.g., ERY-TAB®)

What should I avoid while taking KALYDECO?

  • KALYDECO can cause dizziness in some people who take it. Do not drive a car, use machinery, or do anything that needs you to be alert until you know how KALYDECO affects you
  • You should avoid food containing grapefruit while you are taking KALYDECO

What are the possible side effects of KALYDECO?

KALYDECO can cause serious side effects.

High liver enzymes in the blood have been reported in patients receiving KALYDECO. Your doctor will do blood tests to check your liver:

  • before you start KALYDECO
  • every 3 months during your first year of taking KALYDECO
  • every year while you are taking KALYDECO

For patients who have had high liver enzymes in the past, the doctor may do blood tests to check the liver more often.

Call your doctor right away if you have any of the following symptoms of liver problems:

  • pain or discomfort in the upper right stomach (abdominal) area
  • yellowing of your skin or the white part of your eyes
  • loss of appetite
  • nausea or vomiting
  • dark, amber-colored urine

Abnormality of the eye lens (cataract) has been noted in some children and adolescents receiving KALYDECO. Your doctor should perform eye examinations prior to and during treatment with KALYDECO to look for cataracts.

The most common side effects of KALYDECO include:

  • headache
  • upper respiratory tract infection (common cold), including sore throat, nasal or sinus congestion, runny nose
  • stomach (abdominal) pain
  • diarrhea
  • rash
  • nausea
  • dizziness

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of KALYDECO. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You are encouraged to report side effects to FDA at 1-800-FDA-1088.

For further information, please see full Prescribing Information, including Patient Information.

People with CF pictured may or may not be taking KALYDECO.