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These materials are intended to help you understand more about cystic fibrosis (CF) and treatment with KALYDECO® (ivacaftor). However, they should not replace discussions with your CF care team. Talk with your healthcare provider if you have any questions about KALYDECO or CF.

What to know about KALYDECO oral granules and tablets brochure

If you are interested in learning more about KALYDECO, including how it was studied, click below.

How to take KALYDECO oral granules and tablets brochure

Have some questions about taking KALYDECO? Want suggestions for fat-containing foods to eat with your dose? This handy guide provides instructions for taking KALYDECO oral granules and tablets, answers to frequently asked questions, and even a few recipes to try.


What is KALYDECO® (ivacaftor)?

KALYDECO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients age 2 years and older who have at least one mutation in their CF gene that is responsive to KALYDECO.

Talk to your doctor to learn if you have an indicated CF gene mutation.

It is not known if KALYDECO is safe and effective in children under 2 years of age.

Important Safety Information

Who should not take KALYDECO?

Do not take KALYDECO if you take certain medicines or herbal supplements such as: the antibiotics rifampin (Rifamate®, Rifater®) or rifabutin (Mycobutin®); seizure medications such as phenobarbital, carbamazepine (Tegretol®, Carbatrol®, Equetro®) or phenytoin (Dilantin®, Phenytek®); or St. John’s wort.

Talk to your doctor before taking KALYDECO if you take any of these medicines or supplements.