Do you know about Vertex Guidance & Patient Support?

Vertex Guidance & Patient Support (Vertex GPS™) provides one-on-one reimbursement and product education support during and after therapy initiation to eligible people who have enrolled in the program. This includes information about insurance coverage and financial assistance for people who are 2 years of age and older who have at least one mutation in their CF gene that is responsive to KALYDECO®. Caregivers of patients younger than 18 years of age must be the patient's parent or legal guardian.

If you have been prescribed KALYDECO and want to enroll, please talk to your healthcare provider. If you are enrolled and want to speak with a trained Case Manager to learn more, call 1-877-752-5933 (press 2), Monday through Friday, from 8:30 AM to 7:00 PM ET.

Visit Vertex GPS at


What is KALYDECO® (ivacaftor)?

KALYDECO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients age 2 years and older who have at least one mutation in their CF gene that is responsive to KALYDECO.

Talk to your doctor to learn if you have an indicated CF gene mutation.

It is not known if KALYDECO is safe and effective in children under 2 years of age.

Important Safety Information

Who should not take KALYDECO?

Do not take KALYDECO if you take certain medicines or herbal supplements such as: the antibiotics rifampin (Rifamate®, Rifater®) or rifabutin (Mycobutin®); seizure medications such as phenobarbital, carbamazepine (Tegretol®, Carbatrol®, Equetro®) or phenytoin (Dilantin®, Phenytek®); or St. John’s wort.

Talk to your doctor before taking KALYDECO if you take any of these medicines or supplements.