Taking KALYDECO® (ivacaftor) with Fat-containing Foods

Always take KALYDECO with fat-containing food. Fat-containing food helps the body absorb KALYDECO better. Your doctor can help you choose healthy fat-containing meals and snacks.

Here are some ideas to get you started.

Try these fat-containing snack and meal recipes.

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*These lists are not intended to be complete.

Visit NDB.nal.usda.gov/ndb/search/list for lists of foods and their fat content.

Doctor Dietitian Callout

What is KALYDECO® (ivacaftor)?

KALYDECO is a prescription medicine used for the treatment of cystic fibrosis (CF) in patients age 2 years and older who have one of the following mutations in their CF gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N, or S549R.

KALYDECO is used for the treatment of CF in patients age 2 years and older who have an R117H mutation in their CF gene.

KALYDECO is not for use in people with CF due to other mutations in the CF gene. KALYDECO is not effective in patients with CF with two copies of the F508del mutation (F508del/F508del) in the CF gene.

It is not known if KALYDECO is safe and effective in children under 2 years of age.

Important Safety Information

Who should not take KALYDECO?

Do not take KALYDECO if you take certain medicines or herbal supplements such as: the antibiotics rifampin (Rifamate®, Rifater®) or rifabutin (Mycobutin®); seizure medications such as phenobarbital, carbamazepine (Tegretol®, Carbatrol®, Equetro®) or phenytoin (Dilantin®, Phenytek®); or St. John’s wort.

Talk to your doctor before taking KALYDECO if you take any of these medicines or supplements.